Synthetic approaches to physiologically active polycyclic compounds: VII. Synthesis of 2-(7-Hydroxybicyclo-[3.3.1]non-3-ylmethyl)propane-1,3-diol

被引：0
作者：
O. N. Zefirova
E. V. Nurieva
V. N. Nuriev
A. A. Ivanov
N. V. Zyk
N. S. Zefirov
机构：
[1] Moscow State University,Faculty of Chemistry
[2] Russian Academy of Sciences,Institute of Physiologically Active Substances
来源：
Russian Journal of Organic Chemistry | 2008年 / 44卷
关键词：
Hydroxy Ester; Dimethyl Malonate; Malonate Sodium; Methanesulfonyl Chloride; Ethylenediammonium;
D O I：
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中图分类号：
学科分类号：
摘要：
2-(endo-7-Hydroxybicyclo[3.3.1]non-exo-3-ylmethyl)propane-1,3-diol was synthesized in seven steps starting from endo-7-hydroxybicyclo[3.3.1]nonane-exo-3-carboxylic acid. The title compound attracts interest as intermediate product for the synthesis of potential tubulin ligands.
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页码：1134 / 1138
页数：4
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