The action modes of Lippia sidoides (Cham) essential oil as penetration enhancers on snake skin

被引：0
作者：
M. B. Brito
Gabriela B. Barin
A. A. S. Araújo
D. P. de Sousa
S. C. H. Cavalcanti
Ana Amélia M. Lira
Rogéria S. Nunes
机构：
[1] Universidade Federal de Sergipe,Departamento de Fisiologia
[2] Universidade Federal de Sergipe,Laboratório de Síntese e Aplicação de Materiais
[3] Av. Marechal Rondon,undefined
[4] s/n,undefined
[5] Cidade Universitária,undefined
来源：
Journal of Thermal Analysis and Calorimetry | 2009年 / 97卷
关键词：
DSC; essential oil; FTIR; Lippia sidoides; penetration enhancers;
D O I：
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中图分类号：
学科分类号：
摘要：
The aim of this work was to study the effect of Lippia sidoides essential oil (LSEO) on stratum corneum lipids and the permeation of salicylic acid. DSC and FTIR spectroscopy were applied. LSEO 1% (v/v) significantly enhanced salicylic acid flux through snake skin. According to the DSC curves changes in the transition temperature of the lipids were observed indicating that LSEO can interact with stratum corneum. The IR spectrum of skin treated with LSEO showed a decrease in the peak intensity for CH2 stretchings (2920–2850 cm–1) however the peak positions did not alter suggesting the extraction of the lipids.
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页码：323 / 327
页数：4
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