Characterization of preclinical Alzheimer’s disease model: spontaneous type 2 diabetic cynomolgus monkeys with systemic pro-inflammation, positive biomarkers and developing AD-like pathology

被引:0
作者
Xinxin Huang
Shanshan Huang
Fangyan Fu
Junzhen Song
Yuling Zhang
Feng Yue
机构
[1] Hainan University,State Key Laboratory of Digital Medical Engineering, School of Biomedical Engineering
[2] Hainan University,Collaborative Innovation Center of One Health
[3] Hainan University,undefined
来源
Alzheimer's Research & Therapy | / 16卷
关键词
Alzheimer’s disease; Type 2 diabetes mellitus; Preclinical; Pro-inflammatory factor; Biomarkers; Cynomolgus monkeys;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 212 条
[41]  
Bateman RJ(2022)A TNF receptor 2 agonist ameliorates neuropathology and improves cognition in an Alzheimer’s disease mouse model Proc Natl Acad Sci U S A 119 e2201137119-undefined
[42]  
Xiong C(2021)TNF-mediated neuroinflammation is linked to neuronal necroptosis in Alzheimer’s disease hippocampus Acta Neuropathol Commun 9 159-undefined
[43]  
Benzinger TL(2023)Advances in peripheral blood biomarkers of patients with Alzheimer’s disease: moving closer to personalized therapies Biomed Pharmacother 165 115094-undefined
[44]  
Fagan AM(2002)Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer’s disease Acta Neuropathol 103 26-undefined
[45]  
Goate A(2021)Microglia, and lipids in Alzheimer’s Disease Front Neurosci 15 778822-undefined
[46]  
Fox NC(undefined)undefined undefined undefined undefined-undefined
[47]  
Fagan AM(undefined)undefined undefined undefined undefined-undefined
[48]  
Xiong C(undefined)undefined undefined undefined undefined-undefined
[49]  
Jasielec MS(undefined)undefined undefined undefined undefined-undefined
[50]  
Bateman RJ(undefined)undefined undefined undefined undefined-undefined