Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

被引:0
作者
Edward A Miao
Irina A Leaf
Piper M Treuting
Dat P Mao
Monica Dors
Anasuya Sarkar
Sarah E Warren
Mark D Wewers
Alan Aderem
机构
[1] Institute for Systems Biology,Department of Comparative Medicine
[2] University of Washington,Department of Immunology
[3] Pulmonary,undefined
[4] Critical Care,undefined
[5] Allergy and Sleep Medicine,undefined
[6] The Dorothy M. Davis Heart and Lung Research Institute,undefined
[7] Ohio State University,undefined
[8] University of Washington,undefined
来源
Nature Immunology | 2010年 / 11卷
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摘要
Pyroptosis is a form of proinflammatory cell suicide whose physiological importance is unclear. Aderem and colleagues show that pyroptosis can be integral to protection against bacterial infection.
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页码:1136 / 1142
页数:6
相关论文
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