An Overview of Novel Therapies for Acute Hereditary Angioedema

被引：0
作者：
Rafael Firszt
Michael M. Frank
机构：
[1] Duke University Medical Center,Department of Pediatrics
来源：
American Journal of Clinical Dermatology | 2010年 / 11卷
关键词：
Angioedema; Tranexamic Acid; Fresh Freeze Plasma; Hereditary Angioedema; Icatibant;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Hereditary angioedema is an episodic swelling disorder with autosomal dominant inheritance. Attacks are characterized by nonpitting edema of external or mucosal body surfaces. Patients often present with swelling of the extremities, abdominal pain, and swelling of the mouth and throat, which can at times lead to asphyxiation. The disease is caused by a mutation in the gene encoding the complement C1-inhibitor protein, which leads to unregulated production of bradykinin.
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页码：383 / 388
页数：5
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