Clinical implications of coronary pressure measurement after stent implantation

被引：16
作者：
Matsuo A. [1 ]
Fujita H. [1 ]
Tanigaki T. [1 ]
Shimonaga T. [1 ]
Ueoka A. [1 ]
Tsubakimoto Y. [1 ]
Sakatani T. [1 ]
Kimura S. [1 ]
Inoue K. [1 ]
Kitamura M. [1 ]
机构：
[1] Department of Cardiology, Kyoto Second Red Cross Hospital, 355-5 Haruobi-cho, Kamanzadorimarutamachi, Kamigyo-ku, Kyoto
来源：
Cardiovascular Intervention and Therapeutics | 2013年 / 28卷 / 2期
关键词：
Fractional flow reserve; Stent optimization; Target lesion revascularization;
D O I：
10.1007/s12928-012-0147-7
中图分类号：
学科分类号：
摘要：
This study investigated the effect of fractional flow reserve (FFR) after stent implantation on clinical outcomes. Pressurewire measurements and follow-up data were obtained after stent implantation. Regarding the end point, target lesion revascularization (TLR) occurred in 11 patients (15. 9 %). Patients with TLR had higher frequencies of multiple stenting (54. 5 vs. 19. 0 %, p = 0. 01), lower post-interventional FFRs (0. 84 vs. 0. 88, p = 0. 01), and longer stent lengths (42. 20 vs. 27. 69 mm, p = 0. 01) than patients without TLR. The post-interventional FFR cutoff for TLR was 0. 79, although this value had a weak discriminatory ability. However, multivariate analysis did not show any significant independent predictors of TLR (odds ratio 6. 33; confidence interval 0. 75-53. 4, p = 0. 09). Post-interventional FFR values were not significantly associated with TLR when a sub-analysis was performed in patients who underwent only drug-eluting stent (DES) implantation. It was difficult to achieve post-interventional FFRs of 0. 9 or greater. DES implantation eliminated the effect of post-interventional FFR on TLR. Post-interventional FFR was not able to predict TLR in the present study. © 2012 Japanese Association of Cardiovascular Intervention and Therapeutics.
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页码：170 / 177
页数：7
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