A systematic review of the effects of e-cigarette use on lung function

被引：0
作者：
Lucy Honeycutt
Katherine Huerne
Alanna Miller
Erica Wennberg
Kristian B. Filion
Roland Grad
Andrea S. Gershon
Carolyn Ells
Genevieve Gore
Andrea Benedetti
Brett Thombs
Mark J. Eisenberg
机构：
[1] Jewish General Hospital/McGill University,Lady Davis Institute for Medical Research
[2] McGill University,Biomedical Ethics Unit, Departments of Medicine and Social Studies of Medicine, and Division of Experimental Medicine
[3] McGill University,Departments of Medicine and of Epidemiology, Biostatistics and Occupational Health
[4] McGill University,Department of Family Medicine
[5] Sunnybrook Health Sciences Centre and the University of Toronto,Division of Respirology, Department of Medicine
[6] McGill University,Schulich Library of Physical Sciences, Life Sciences, and Engineering
[7] Research Institute of the McGill University Health Centre,Respiratory Epidemiology and Clinical Research Unit, Centre for Outcomes Research and Evaluation
[8] McGill University,Departments of Psychiatry, Psychology, and Biomedical Ethics Unit
[9] Jewish General Hospital/McGill University,Division of Cardiology
来源：
npj Primary Care Respiratory Medicine | / 32卷
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摘要：
Given the increasing use of e-cigarettes and uncertainty surrounding their safety, we conducted a systematic review to determine the effects of e-cigarettes on measures of lung function. We systematically searched EMBASE, MEDLINE, and PsycINFO databases via Ovid, the Cochrane CENTRAL database, and the Web of Science Core from 2004 until July 2021, identifying 8856 potentially eligible studies. A total of eight studies (seven studying immediate effects and one long-term effects, 273 total participants) were included. The risk of bias was assessed using the Risk of Bias in Non-randomized Studies—of Interventions (ROBINS-I) and Cochrane risk of bias tools. These studies suggest that vaping increases airway resistance but does not appear to impact forced expiratory volume in one second (FEV1), forced vital capacity (FVC), or FEV1/FVC ratio. However, given the limited size and follow-up duration of these studies, larger, long-term studies are required to further determine the effects of e-cigarettes on lung function.
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