Aedes aegypti Totivirus identified in mosquitoes in the Brazilian Amazon region

被引：0
作者：
Élcio Leal
Edcelha Soares D.’Athaide Ribeiro
Fred Julio Costa Monteiro
Julia Pantoja Marques
Diuliana dos Santos Mendes
Vanessa S. Morais
Emerson Luiz Lima Araújo
Ramendra Pati Pandey
Chung-Ming Chang
Xutao Deng
Eric Delwart
Antonio Charlys da Costa
Kledoaldo Lima
机构：
[1] Universidade Federal Do Pará,Laboratório de Diversidade Viral, Instituto de Ciências Biológicas
[2] Health Surveillance Superintendence of Amapa,Public Health Laboratory of Amapa—LACEN/AP
[3] Universidade de São Paulo,Faculdade de Medicina, Instituto de Medicina Tropical
[4] Secretariat of the Ministry of Health (CGLAB/DAEVS/SVS-MS),General Coordination of Public Health Laboratories of the Strategic Articulation, Department of the Health Surveillance
[5] SRM University,Centre for Drug Design Discovery and Development (C4D)
[6] Delhi-NCR,Master & Ph.D. Program in Biotechnology Industry
[7] Chang Gung University,Department Laboratory Medicine
[8] Vitalant Research Institute,Hospital das Clínicas
[9] University of California San Francisco,undefined
[10] Federal University of Pernambuco,undefined
[11] European Virus Bioinformatics Center,undefined
[12] Faculdade Pernambucana de Saúde,undefined
来源：
Virus Genes | 2023年 / 59卷
关键词：
Totivirus; Totiviridae; Aedes; Mosquitoes; Metagenomics; Virome;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The totiviridae family contains viruses with double-stranded RNA genomes of 4.6–7.0 kpb, which encode a capsid protein (CP) and RNA-dependent RNA polymerase (RdRp), and they are approximately 40 nm in diameter with icosahedral symmetry. Totiviruses were first isolated from mosquitoes collected in Shaanxi Province (China). Here, we report a new Aedes aegypti Totivirus (AaTV) identified in mosquitoes from the Amazon rainforest. Mosquitoes (Diptera: Culicidae) were collected from a forest reserve belonging to the Amazon forest in the city of Macapá, Amapá state, Northern Brazil. A viral sequence with a 5748 nucleotide length that was nearly identical to Aedes aegypti Totivirus (AaTV), here named Aedes aegypti Totivirus BR59AP, was detected. A detailed molecular analysis was performed and shows that AaTV-BR59AP is highly related to the AaTV strain from the Caribbean region. We emphasize the importance of the characterization of new viruses in mosquitoes to deepen our understanding of viral diversity in insects and their potential role in disease.
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页码：167 / 172
页数：5
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