Interplay between Inflammaging, Frailty and Nutrition in Covid-19: Preventive and Adjuvant Treatment Perspectives

被引：0
作者：
A. Padilha de Lima
M. Macedo Rogero
T. Araujo Viel
H. M. Garay-Malpartida
I. Aprahamian
Sandra Maria Lima Ribeiro
机构：
[1] University of São Paulo,School of Medicine
[2] Faculty IELUSC,School of Physical Education
[3] University of São Paulo,Public Health School
[4] University of São Paulo,School of Arts, Sciences and Humanities
[5] Jundiaí Medical School,Department of Internal Medicine and Division of Geriatrics
来源：
The journal of nutrition, health & aging | 2022年 / 26卷
关键词：
COVID-19; inflammaging; nutritional risk; diet; probiotics; senolytics;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
As humans age, their immune system undergoes modifications, including a low-grade inflammatory status called inflammaging. These changes are associated with a loss of physical and immune resilience, amplifying the risk of being malnourished and frail. Under the COVID-19 scenario, inflammaging increases the susceptibility to poor prognostics. We aimed to bring the current concepts of inflammaging and its relationship with frailty and COVID-19 prognostic; highlight the importance of evaluating the nutritional risk together with frailty aiming to monitor older adults in COVID-19 scenario; explore some compounds with potential to modulate inflammaging in perspective to manage the COVID-19 infection. Substances such as probiotics and senolytics can help reduce the high inflammatory status. Also, the periodic evaluation of nutrition risk and frailty will allow interventions, assuring the appropriate care.
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页码：67 / 76
页数：9
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