Next-generation sequencing to monitor the spread of antimicrobial resistance

被引：0
作者：
Michael Otto
机构：
[1] Pathogen Molecular Genetics Section,
[2] Laboratory of Bacteriology,undefined
[3] National Institute of Allergy and Infectious Diseases,undefined
[4] U.S. National Institutes of Health,undefined
来源：
Genome Medicine | / 9卷
关键词：
Antibiotic resistance; ESBL; MRSA; Next-generation sequencing;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Next-generation sequencing is increasingly being used to monitor current and historic events related to the emergence and spread of antimicrobial resistance. In a recent publication, researchers analyzed the rise of methicillin-resistant Staphylococcus aureus in the 1960s, emphasizing that adaptations conferring antibiotic resistance might pre-date the introduction of novel antibiotic derivatives. Other researchers have evaluated the role of transmission within a healthcare network, using the example of extended-spectrum beta-lactamase-resistant Escherichia coli.
引用
收藏
相关论文
共 20 条
  • [1] Barber M(1948)Infection by penicillin-resistant staphylococci Lancet 2 641-4
  • [2] Rozwadowska-Dowzenko M(2013)National burden of invasive methicillin-resistant JAMA Intern Med 173 1970-8
  • [3] Dantes R(2015) infections, United States, 2011 BMC Infect Dis 15 168-11
  • [4] Mu Y(2013)Colonisation with ESBL-producing and carbapenemase-producing Enterobacteriaceae, vancomycin-resistant enterococci, and meticillin-resistant Bioessays 35 4-71
  • [5] Belflower R(2017) in a long-term care facility over one year Nat Rev Drug Discov 16 457-71
  • [6] Aragon D(2009)Coagulase-negative staphylococci as reservoirs of genes facilitating MRSA infection: Staphylococcal commensal species such as Infect Dis Clin North Am 23 153-undefined
  • [7] Dumyati G(undefined) are being recognized as important sources of genes promoting MRSA colonization and virulence undefined undefined undefined-undefined
  • [8] Harrison LH(undefined)Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance undefined undefined undefined-undefined
  • [9] Ludden C(undefined)Staphylococcal vaccines and immunotherapies undefined undefined undefined-undefined
  • [10] Cormican M(undefined)undefined undefined undefined undefined-undefined
12