Training ribozymes to switch

被引：0
|
作者：
Kristin A. Marshall
Andrew D. Ellington
机构：
[1] Institute for Cellular and Molecular Biology,the Department of Chemistry and Biochemistry
[2] University of Texas at Austin,undefined
来源：
Nature Structural Biology | 1999年 / 6卷
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学科分类号：
摘要：
Ribozymes that are sensitive to cyclic nucleotides have been selected in vitro. Remarkably, the cGMP-dependent ribozymes are specifically activated by a factor of 5,000 — the largest allosteric ribozyme activation by a small molecule seen to date.
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页码：992 / 994
页数：2
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