Excretion of Compound M-11 and Its Metabolites with Urine and Feces in Rats

被引:0
|
作者
D. V. Bastrygin
A. O. Viglinskaya
G. B. Kolyvanov
A. A. Litvin
P. O. Bochkov
T. Ya. Mozhaeva
V. P. Zherdev
机构
[1] Russian Academy of Medical Sciences,Laboratory of Pharmacokinetics, V. V. Zakusov Institute of Pharmacology
来源
Bulletin of Experimental Biology and Medicine | 2012年 / 153卷
关键词
excretion; compound M-11; metabolites;
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中图分类号
学科分类号
摘要
The excretion of compound M-11 and its metabolites with the urine and feces was studied in rats after intraperitoneal and oral administration in a dose of 25 mg/kg. Experiments showed that 1% metabolites were detected in excretions over 24 h irrespective of the route of administration, while the initial compound was not found even in trace amounts.
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页码:707 / 709
页数:2
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