MiR-221/SIRT1/Nrf2 signal axis regulates high glucose induced apoptosis in human retinal microvascular endothelial cells

被引：0
|
作者：
Bin Chen
Li Wu
Ting Cao
Hong-Mei Zheng
Tao He
机构：
[1] Renmin Hospital of Wuhan University,Department of Ophthalmology
来源：
BMC Ophthalmology | / 20卷
关键词：
Diabetic retinopathy; miR-221; SIRT1; Nrf2; hRMEC;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] The interface targeting hnRNPA2B1 regulates the repression of transthyretin against human retinal microvascular endothelial cells in high-glucose environment
    Tian, Yikun
    Ye, Lu
    Shao, Jun
    Xin, Yu
    DIABETIC MEDICINE, 2023, 40 (09)
  • [22] Circ_0001897 regulates high glucose-induced angiogenesis and inflammation in retinal microvascular endothelial cells through miR-29c-3p/transforming growth factor beta 2 axis
    Gong, Yudan
    Li, Xinze
    Xie, Liuyi
    BIOENGINEERED, 2022, 13 (05) : 11694 - 11705
  • [23] miR-29a/b cluster suppresses high glucose-induced endothelial-mesenchymal transition in human retinal microvascular endothelial cells by targeting Notch2
    Zhang, Jiayu
    Zeng, Yue
    Chen, Jiawei
    Cai, Daqiu
    Chen, Chengwei
    Zhang, Sifang
    Chen, Zhenguo
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019, 17 (04) : 3108 - 3116
  • [24] MicroRNA-29b-3p Promotes Human Retinal Microvascular Endothelial Cell Apoptosis via Blocking SIRT1 in Diabetic Retinopathy
    Zeng, Yong
    Cui, Zekai
    Liu, Jian
    Chen, Jiansu
    Tang, Shibo
    FRONTIERS IN PHYSIOLOGY, 2020, 10
  • [25] Idebenone regulates sirt1/Nrf2/TNF-α pathway with inhibition of oxidative stress, inflammation, and apoptosis in testicular torsion/detorsion in juvenile rats
    Abdelzaher, Walaa Yehia
    Mostafa-Hedeab, Gomaa
    Sayed Abo Bakr Ali, Abdel Hamid
    Fawzy, Michael Atef
    Ahmed, Amira F.
    Bahaa El-deen, Mohamed Ahmed
    Welson, Nermeen N.
    Aly Labib, Dina A.
    HUMAN & EXPERIMENTAL TOXICOLOGY, 2022, 41
  • [26] SIRT3 mitigates high glucose-induced damage in retinal microvascular endothelial cells via OPA1-mediated mitochondrial dynamics
    Shi, Jiemei
    Liu, Min
    Zhu, Haohao
    Jiang, Chunhui
    EXPERIMENTAL CELL RESEARCH, 2025, 444 (02)
  • [27] TGF-β1 Mediates the EndoMt in High Glucose-Treated Human Retinal Microvascular Endothelial Cells
    Ying, Jia
    Wang, Peipei
    Jin, Xiao
    Luo, Li
    Lai, Keshuang
    Li, Jun
    SEMINARS IN OPHTHALMOLOGY, 2024, 39 (04) : 312 - 319
  • [28] LncRNA MIR497HG inhibits proliferation and migration of retinal endothelial cells under high-level glucose treatment via miRNA-128-3p/SIRT1 axis
    Yang, J.
    Yang, F-J
    Wang, Y-G
    Su, G-F
    Mao, X.
    EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2020, 24 (11) : 5871 - 5877
  • [29] Melatonin alleviates doxorubicin-induced cardiotoxicity via inhibiting oxidative stress, pyroptosis and apoptosis by activating Sirt1/Nrf2 pathway
    Zhang, Wei
    Wang, Xi
    Tang, Yanhong
    Huang, Congxin
    BIOMEDICINE & PHARMACOTHERAPY, 2023, 162
  • [30] MiR-182-5p Regulates Chondrocyte Inflammation and Oxidative Stress to Promote Osteoarthritis through Targeting the SIRT1/Nrf2 Signaling Pathway
    Yang, Cheng
    Gu, Xiao-Peng
    Zhang, Teng
    Hu, Hong
    Bai, Jie
    JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS, 2023, 37 (06) : 3197 - 3206
12345