The role of vitamin D deficiency in the pathogenesis of osteoporosis and in the modulation of the immune system in HIV-infected patients

被引：5

作者：

Allison C. Ross

Grace A. McComsey

机构：

[1] Department of Pediatrics, Emory University, School of Medicine, Atlanta, GA 30322

[2] Children's Healthcare of Atlanta, Atlanta, GA

[3] Rainbow Babies and Children's Hospital, Case Western Reserve University, Cleveland, OH

来源：

Clinical Reviews in Bone and Mineral Metabolism | 2012年 / 10卷 / 4期

关键词：

1,25-Dihydroxyvitamin D; 25-Hydroxyvitamin D; Bone mineral density; HIV; Immune restoration; Immune system; Osteopenia; Osteoporosis; Vitamin D deficiency;

D O I：

10.1007/s12018-012-9131-0

中图分类号：

学科分类号：

摘要：

Vitamin D deficiency is widespread among HIV-infected adults and children. Vitamin D deficiency may contribute to the risk of developing the long-term complications of HIV infection, such as osteoporosis. Vitamin D is also known to play an important role in the immune system and may affect HIV disease progression and/or CD4 cell counts. This article will review the current data on the role of vitamin D deficiency in the pathogenesis of osteoporosis and in the modulation of the immune system in HIV-infected patients. © 2012 Springer Science+Business Media, LLC.

引用

页码：277 / 287

页数：10

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