Complete genome sequence of thermophilic Bacillus smithii type strain DSM 4216T

被引：0
作者：
Elleke F. Bosma
Jasper J. Koehorst
Sacha A. F. T. van Hijum
Bernadet Renckens
Bastienne Vriesendorp
Antonius H. P. van de Weijer
Peter J. Schaap
Willem M. de Vos
John van der Oost
Richard van Kranenburg
机构：
[1] Wageningen University,Laboratory of Microbiology
[2] Technical University of Denmark,Present address: The Novo Nordisk Foundation Center for Biosustainability
[3] Wageningen University,Laboratory of Systems and Synthetic Biology
[4] CMBI,undefined
[5] NCMLS,undefined
[6] Corbion,undefined
来源：
Standards in Genomic Sciences | / 11卷
关键词：
Genome sequence; Lactic acid; Thermophile; Thermophilic bacillus; Biotechnology;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Bacillus smithii is a facultatively anaerobic, thermophilic bacterium able to use a variety of sugars that can be derived from lignocellulosic feedstocks. Being genetically accessible, it is a potential new host for biotechnological production of green chemicals from renewable resources. We determined the complete genomic sequence of the B. smithii type strain DSM 4216T, which consists of a 3,368,778 bp chromosome (GenBank accession number CP012024.1) and a 12,514 bp plasmid (GenBank accession number CP012025.1), together encoding 3880 genes. Genome annotation via RAST was complemented by a protein domain analysis. Some unique features of B. smithii central metabolism in comparison to related organisms included the lack of a standard acetate production pathway with no apparent pyruvate formate lyase, phosphotransacetylase, and acetate kinase genes, while acetate was the second fermentation product.
引用
收藏
相关论文
共 194 条
  • [1] Hammer B(1915)Bacteriological studies on the coagulation of evaporated milk Iowa Agricultural Experimental Station Research Bulletin 19 119-131
  • [2] Nakamura LK(1988)Taxonomic Study of Int J Syst Bacteriol 38 63-73
  • [3] Blumenstock I(2015) Hammer 1915 with a Proposal for Appl Environ Microbiol 81 1874-1883
  • [4] Claus D(2015)Isolation and screening of thermophilic bacilli from compost for electrotransformation and fermentation: Characterization of Microb Cell Fact 14 99-385
  • [5] Bosma EF(2009) ET 138 as a new biocatalyst Appl Biochem Biotechnol 155 379-379
  • [6] van de Weijer AHP(2013)Establishment of markerless gene deletion tools in thermophilic Curr Biotechnol 2 360-405
  • [7] Daas MJA(2009) and construction of multiple mutant strains Trends Biotechnol 27 398-2016
  • [8] van der Oost J(2014)Thermophilic Biochim Biophys Acta 1837 2004-293
  • [9] de Vos WM(2014) requires less cellulases for simultaneous saccharification and fermentation of cellulose to products than mesophilic microbial biocatalysts Bioresour Technol 162 283-1591
  • [10] van Kranenburg R(2011)Sustainable production of bio-based chemicals by extremophiles J Appl Microbiol 110 1584-565
12345678910