Repurposing thioridazine for inducing immunogenic cell death in colorectal cancer via eIF2α/ATF4/CHOP and secretory autophagy pathways

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作者
Thu-Ha Tran
Ming Kao
Hsiao-Sheng Liu
Yi-Ren Hong
Yeu Su
Chi-Ying F. Huang
机构
[1] National Yang Ming Chiao Tung University and Academia Sinica,Taiwan International Graduate Program in Molecular Medicine
[2] National Yang Ming Chiao Tung University,Institute of Biopharmaceutical Sciences
[3] National Cheng Kung University,Department of Microbiology and Immunology, College of Medicine
[4] Kaohsiung Medical University,Center for Cancer Research, College of Medicine
[5] M. Sc. Program in Tropical Medicine,Graduate Institutes of Medicine, College of Medicine
[6] College of Medicine,Department of Biological Sciences
[7] Kaohsiung Medical University,Department of Medical Research
[8] Kaohsiung Medical University,Department of Biochemistry, College of Medicine
[9] National Sun Yat-Sen University,Institute of Clinical Medicine, College of Medicine
[10] Kaohsiung Medical University Hospital,Department of Biotechnology and Laboratory Science in Medicine
[11] Neuroscience Research Center,undefined
[12] Kaohsiung Medical University,undefined
[13] Kaohsiung Medical University,undefined
[14] National Yang Ming Chiao Tung University,undefined
[15] National Yang Ming Chiao Tung University,undefined
来源
Cell Communication and Signaling | / 21卷
关键词
Colorectal cancer; Thioridazine; Immunogenic cell death; Endoplasmic reticulum stress; Secretory autophagy;
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