FSH receptor polymorphisms and controlled ovarian stimulation [FSH-Rezeptor-Polymorphismen und kontrollierte ovarielle Stimulation]

被引:0
|
作者
Cordes A. [1 ]
Kiesel L. [1 ]
Schüring A. [1 ]
机构
[1] UKM Kinderwunschzentrum, Klinik für Frauenheilkunde und Geburtshilfe, Universitätsklinikum Münster, Albert-Schweitzer Campus 1, D11, Münster
关键词
Assisted reproduction; Birth rate; Pregnancy; Receptor sensitivity; Stimulation therapy;
D O I
10.1007/s10304-015-0007-5
中图分类号
学科分类号
摘要
Genetic polymorphisms of the gonadotropin axis have been investigated in recent years to predict the ovarian response to stimulation protocols in assisted reproductive technology (ART) programs. The follicle-stimulating hormone (FSH) receptor polymorphism Asn680Ser is the best studied genetic factor with respect to ART. This review article summarizes the current state of knowledge against the background of the available evidence and gives an outlook on possible future clinical applications of genetic polymorphisms of the FSH axis. © 2015, Springer-Verlag Berlin Heidelberg.
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页码:98 / 101
页数:3
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