Neonatal Hypoglycemia

被引：0
作者：
Ved Bhushan Arya
Senthil Senniappan
Maria Guemes
Khalid Hussain
机构：
[1] University College London Institute of Child Health,Clinical and Molecular Genetics Unit
[2] London Centre for Pediatric Endocrinology,London Centre for Pediatric Endocrinology
[3] Great Ormond Street Hospital for Children,Developmental Endocrinology Research Group, Clinical and Molecular Genetics Unit
[4] Great Ormond Street Hospital for Children,undefined
[5] University College London Institute of Child Health,undefined
来源：
The Indian Journal of Pediatrics | 2014年 / 81卷
关键词：
Neonatal hypoglycemia; Congenital hyperinsulinism; Glycogen storage disorders;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Glucose is essential for cerebral metabolism. Unsurprisingly therefore, hypoglycemia may result in encephalopathy. Knowledge of the homeostatic mechanisms that maintain blood glucose concentrations within a tight range is the key for diagnosis and appropriate management of hypoglycemia. Neonatal hypoglycemia can be transient and is commonly observed in at-risk infants. A wide range of rare endocrine and metabolic disorders can present with neonatal hypoglycemia, of which congenital hyperinsulinism is responsible for the most severe form of hypoglycemia. Collection of appropriate blood samples for hormones and intermediary metabolites during an episode of hypoglycemia is critical for diagnosis and appropriate management. Prompt diagnosis with aggressive early intervention remains the mainstay of treatment to avert irreversible brain damage.
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页码：58 / 65
页数：7
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