Regulation of alternative macrophage activation by chromatin remodeling

被引：0
|
作者：
Scott Bowdridge
William C Gause
机构：
[1] Scott Bowdridge and William C. Gause are at the Center for Immunity and Inflammation,
[2] New Jersey Medical School,undefined
[3] University of Medicine and Dentistry,undefined
[4] Newark,undefined
[5] New Jersey,undefined
[6] USA.,undefined
来源：
Nature Immunology | 2010年 / 11卷
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摘要：
The regulation of gene expression through changes in chromatin structure is increasingly recognized as a chief component of activation of cells of the immune response. It now seems that histone demethylation of the promoter of the gene encoding the transcription factor IRF4 contributes to alternative macrophage activation.
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页码：879 / 881
页数：2
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