Myocardial Salvage after Reduced-Dose Thrombolysis Combined with Glycoprotein IIb/IIIa Blockade Versus Thrombolysis Alone in Patients with Acute Myocardial Infarction

被引:0
作者
Gjin Ndrepepa
Julinda Mehilli
Markus Schwaiger
Stephan Nekolla
Claus Schmitt
Josef Dirschinger
Albert Schömig
Adnan Kastrati
机构
[1] The Deutsches Herzzentrum,The Medizinische Klinik rechts der Isar
[2] The Klinik und Poliklinik für Nuklearmedizin rechts der Isar,The Deutsches Herzzentrum; The Medizinische Klinik rechts der Isar
[3] Technische Universität,undefined
[4] Technische Universität,undefined
来源
Journal of Thrombosis and Thrombolysis | 2004年 / 17卷
关键词
acute myocardial infarction; reperfusion; scintigraphy; thrombolysis;
D O I
暂无
中图分类号
学科分类号
摘要
Background: The aim of study was to examine the efficacy of reduced-dose alteplase plus abciximab versus alteplase alone by quantifying the amount of myocardium salvaged using myocardial scintigraphy.
引用
收藏
页码:191 / 197
页数:6
相关论文
共 44 条
[1]  
Fuster V(1986)Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction Lancet 1 397-402
[2]  
Badimon L(1988)Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2 Lancet 2 349-360
[3]  
Badimon JJ(1993)The effects of tissue plasminogen activator, streptokinase, or both on coronaryartery patency, ventricular function, and survival after acute myocardial infarction N Engl J Med 329 1615-1622
[4]  
Chesebro JH.(1992)The pathogenesis of coronary artery disease and the acute coronary syndromes (1) N Engl J Med 326 242-250
[5]  
Furie B(1992)Molecular and cellular biology of blood coagulation N Engl J Med 326 800-806
[6]  
Furie BC.(1998)Toward a new frontier in myocardial reperfu-sion therapy: Emerging platelet preeminence Circulation 97 211-218
[7]  
Topol EJ.(1993)Profound inhibition of platelet aggregation with monoclonal antibody 7E3 Fab after thrombolytic therapy. Results of the Throm-bolysis and Angioplasty in Myocardial Infarction (TAMI) 8 Pilot Study J AmColl Cardiol 22 381-389
[8]  
Kleiman NS(1997)Combined accelerated tissue-plasminogen activator and platelet glycoprotein IIb/IIIa integrin receptor blockade with Integrilin in acute my-ocardial infarction. Results of a randomized, placebo-controlled, dose-ranging trial Circulation 95 846-854
[9]  
Ohman EM(1998)Combining Thrombolysis With the Platelet Glycoprotein IIb/IIIa Inhibitor Lami-fiban: Results of the Platelet Aggregation Receptor An-tagonist Dose Investigation and Reperfusion Gain in My-ocardial Infarction (PARADIGM) Trial J AmColl Cardiol 32 2003-2010
[10]  
Califf RM(1999)Abciximab facilitates the rate and extent of thrombolysis: Results of the thrombolysis in myocardial infarction (TIMI) 14 trial. The TIMI 14 Investigators Circulation 99 2720-2732