Bapineuzumab for mild to moderate Alzheimer’s disease in two global, randomized, phase 3 trials

被引：0

作者：

Rik Vandenberghe

Juha O. Rinne

Mercè Boada

Sadao Katayama

Philip Scheltens

Bruno Vellas

Michael Tuchman

Achim Gass

Jochen B. Fiebach

Derek Hill

Kasia Lobello

David Li

Tom McRae

Prisca Lucas

Iona Evans

Kevin Booth

Gerald Luscan

Bradley T. Wyman

Lisa Hua

Lingfeng Yang

H. Robert Brashear

Ronald S. Black

机构：

[1] Alzheimer Research Centre KU Leuven,University Hospitals Leuven, Department of Neurosciences

[2] University of Turku and Turku University Hospital,Turku PET Centre and Division of Clinical Neurosciences

[3] Fundació ACE,Graduate School of Biomedical Sciences

[4] Barcelona Alzheimer Treatment and Research Center,Alzheimercentrum VUmc, Neurology

[5] Hiroshima University,Department of Neurology, University Hospital Mannheim

[6] VU University Medical Center,undefined

[7] CHU Toulouse,undefined

[8] Gérontopôle,undefined

[9] Palm Beach Neurological Center,undefined

[10] University Medical Centre Mannheim,undefined

[11] Center for Stroke Research Berlin (CSB),undefined

[12] Charité Universitätsmedizin Berlin,undefined

[13] IXICO Ltd.,undefined

[14] The London Bioscience Innovation Centre,undefined

[15] Pfizer Inc.,undefined

[16] Pfizer Inc.,undefined

[17] Pfizer Global Research and Development (PGRD),undefined

[18] Pfizer Ltd.,undefined

[19] Pfizer Inc.,undefined

[20] Janssen Alzheimer Immunotherapy Research & Development,undefined

[21] LLC,undefined

来源：

Alzheimer's Research & Therapy | / 8卷

关键词：

Alzheimer’s disease; Bapineuzumab; Immunotherapy; Amyloid β; Clinical trial; ARIA-E; Vasogenic edema;

D O I：

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[21] Phase 3 solanezumab trials: Secondary outcomes in mild Alzheimer's disease patients [J].

Siemers, Eric R. ;

Sundell, Karen L. ;

Carlson, Christopher ;

Case, Michael ;

Sethuraman, Gopalan ;

Liu-Seifert, Hong ;

Dowsett, Sherie A. ;

Pontecorvo, Michael J. ;

Dean, Robert A. ;

Demattos, Ronald .

ALZHEIMERS & DEMENTIA, 2016, 12 (02) :110-120

[22] Further analyses of the safety of verubecestat in the phase 3 EPOCH trial of mild-to-moderate Alzheimer’s disease [J].

Michael F. Egan ;

Yuki Mukai ;

Tiffini Voss ;

James Kost ;

Julie Stone ;

Christine Furtek ;

Erin Mahoney ;

Jeffrey L. Cummings ;

Pierre N. Tariot ;

Paul S. Aisen ;

Bruno Vellas ;

Christopher Lines ;

David Michelson .

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[23] Acupuncture for patients with mild to moderate Alzheimer's disease: a randomized controlled trial [J].

Jia, Yujie ;

Zhang, Xuezhu ;

Yu, Jianchun ;

Han, Jingxian ;

Yu, Tao ;

Shi, Jiangwei ;

Zhao, Lan ;

Nie, Kun .

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[24] Acupuncture for patients with mild to moderate Alzheimer’s disease: a randomized controlled trial [J].

Yujie Jia ;

Xuezhu Zhang ;

Jianchun Yu ;

Jingxian Han ;

Tao Yu ;

Jiangwei Shi ;

Lan Zhao ;

Kun Nie .

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[25] A Phase IIa Randomized Control Trial of VEL015 ( Sodium Selenate) in Mild-Moderate Alzheimer's Disease [J].

Malpas, Charles B. ;

Vivash, Lucy ;

Genc, Sila ;

Saling, Michael M. ;

Desmond, Patricia ;

Steward, Christopher ;

Hicks, Rodney J. ;

Callahan, Jason ;

Brodtmann, Amy ;

Collins, Steven ;

Macfarlane, Stephen ;

Corcoran, Niall M. ;

Hovens, Christopher M. ;

Velakoulis, Dennis ;

O'Brien, Terence J. .

JOURNAL OF ALZHEIMERS DISEASE, 2016, 54 (01) :223-232

[26] Intepirdine as adjunctive therapy to donepezil for mild-to-moderate Alzheimer's disease: A randomized, placebo-controlled, phase 3 clinical trial (MINDSET) [J].

Lang, Frederick M. ;

Mo, Yi ;

Sabbagh, Marwan ;

Solomon, Paul ;

Boada, Merce ;

Jones, Roy W. ;

Frisoni, Giovanni B. ;

Grimmer, Timo ;

Dubois, Bruno ;

Harnett, Mark ;

Friedhoff, Sarah R. ;

Coslett, Shari ;

Cummings, Jeffrey L. .

ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS, 2021, 7 (01)

[27] Low-dose interleukin-2 in patients with mild to moderate Alzheimer's disease: a randomized clinical trial [J].

Faridar, Alireza ;

Gamez, Nazaret ;

Li, Daling ;

Wang, Yanling ;

Boradia, Reena ;

Thome, Aaron D. ;

Zhao, Weihua ;

Beers, David R. ;

Thonhoff, Jason R. ;

Nakawah, Mohammad O. ;

Roman, Gustavo C. ;

Volpi, John J. ;

Toledo, Jon B. ;

George, Michael ;

Davis, Charles S. ;

Pascual, Belen ;

Grundman, Michael ;

Masdeu, Joseph C. ;

Appel, Stanley H. .

ALZHEIMERS RESEARCH & THERAPY, 2025, 17 (01)

[28] Estimating attrition in mild-to-moderate Alzheimer's disease and mild cognitive impairment clinical trials [J].

Ritchie, Marina ;

Gillen, Daniel L. ;

Grill, Joshua D. .

ALZHEIMERS RESEARCH & THERAPY, 2023, 15 (01)

[29] Estimating attrition in mild-to-moderate Alzheimer’s disease and mild cognitive impairment clinical trials [J].

Marina Ritchie ;

Daniel L. Gillen ;

Joshua D. Grill .

Alzheimer's Research & Therapy, 15

[30] Solanezumab for the treatment of mild-to-moderate Alzheimer's disease [J].

Imbimbo, Bruno P. ;

Ottonello, Simone ;

Frisardi, Vincenza ;

Solfrizzi, Vincenzo ;

Greco, Antonio ;

Seripa, Davide ;

Pilotto, Alberto ;

Panza, Francesco .

EXPERT REVIEW OF CLINICAL IMMUNOLOGY, 2012, 8 (02) :135-149

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