No association of inducible nitric oxide synthase gene (NOS2A) to multiple sclerosis

被引：0

作者：

Yolanda Blanco

Jordi Yagüe

Francesc Graus

Albert Saiz

机构：

[1] Servei de Neurologia,

[2] Hospital Clínic,undefined

[3] Villarroel 170,undefined

[4] Barcelona 08036,undefined

[5] Spain. asaiz@clinic.ub.es,undefined

[6] Immunology,undefined

[7] Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS),undefined

[8] Hospital Clínic,undefined

[9] University of Barcelona,undefined

[10] Barcelona. Spain,undefined

来源：

Journal of Neurology | 2003年 / 250卷

关键词：

Key words multiple sclerosis; nitric oxide; NOS2A promoter;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Nitric oxide (NO) is a nonspecific inflammatory mediator that has been involved in the pathogenesis of multiple sclerosis (MS). The influence of the promoter polymorphism of inducible NO synthase gene (NOS2A) on susceptibility and outcome was studied in 140 MS Spanish patients and 147 healthy controls matched for sex, age, and ethnicity. No association was found between MS susceptibility, course or outcome of the disease, and NOS2A polymorphisms.

引用

页码：598 / 600

页数：2