Effects of Pomegranate Juice Supplementation on Pulse Wave Velocity and Blood Pressure in Healthy Young and Middle-aged Men and Women

被引：0
作者：
Anthony Lynn
Hiba Hamadeh
Wing Chi Leung
Jean M. Russell
Margo E. Barker
机构：
[1] Sheffield Hallam University,Human Nutrition Unit
[2] The University of Sheffield,Corporate Information and Computing Services
[3] The University of Sheffield,undefined
来源：
Plant Foods for Human Nutrition | 2012年 / 67卷
关键词：
Pomegranate juice; Arterial stiffness; Pulse wave velocity; Blood pressure; Polyphenols;
D O I：
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中图分类号：
学科分类号：
摘要：
Pomegranate juice may improve cardiovascular risk because of its content of antioxidant polyphenols. We conducted a randomized placebo-controlled parallel study to examine the effect of pomegranate juice on pulse wave velocity (PWV), blood pressure (BP) and plasma antioxidant status (ferric reducing power; FRAP) in 51 healthy adults (30–50 years). Participants consumed 330 ml/day of pomegranate juice or control drink for four weeks. Measurements were made at baseline and at four weeks. There was no effect of the intervention on PWV (P = 0.694) and plasma FRAP (P = 0.700). However, there was a significant fall in systolic blood pressure (−3.14 mmHg, P < 0.001), diastolic blood pressure (−2.33 mmHg P < 0.001) and mean arterial pressure (−2.60 mmHg, P < 0.001). Change in weight was similar in the two groups over the intervention period (P = 0.379). The fall in BP was not paralleled by changes in concentration of serum angiotensin converting enzyme. We conclude that pomegranate juice supplementation has benefits for BP in the short term, but has no effect on PWV. The mechanism for the effect is uncertain.
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页码：309 / 314
页数：5
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