Combination chemotherapy with intermittent erlotinib and pemetrexed for pretreated patients with advanced non-small cell lung cancer: a phase I dose-finding study

被引:0
作者
Seigo Minami
Takashi Kijima
Ryo Takahashi
Hiroshi Kida
Takeshi Nakatani
Masanari Hamaguchi
Yoshiko Takeuchi
Izumi Nagatomo
Suguru Yamamoto
Isao Tachibana
Kiyoshi Komuta
Ichiro Kawase
机构
[1] Osaka Police Hospital,Department of Respiratory Medicine
[2] Osaka University Graduate School of Medicine,Department of Respiratory Medicine, Allergy and Rheumatic Diseases
[3] Osaka Prefectural Medical Center for Respiratory and Allergic Diseases,undefined
来源
BMC Cancer | / 12卷
关键词
Combination; Erlotinib; Pemetrexed; NSCLC; Phase I;
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  • [1] Jemal A(2010)Cancer statistics, 2010 CA Cancer J Clin 60 277-300
  • [2] Siegel R(2009)American Society of Clinical Oncology Clinical Practice Guideline update on chemotherapy for stage IV non-small-cell lung cancer J Clin Oncol 27 6251-6266
  • [3] Xu J(2009)Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil J Clin Oncol 27 1227-1234
  • [4] Ward E(2006)Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer N Engl J Med 355 2542-2550
  • [5] Azzoli CG(2008)Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer J Clin Oncol 26 3543-3551
  • [6] Baker S(2004)Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy J Clin Oncol 22 1589-1597
  • [7] Temin S(2000)Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy J Clin Oncol 18 2095-2103
  • [8] Pao W(2005)Erlotinib in previously treated non-small-cell lung cancer N Engl J Med 353 123-132
  • [9] Aliff T(2001)Pemetrexed disodium: a novel antifolate clinically active against multiple solid tumors Oncologist 6 363-373
  • [10] Brahmer J(2008)A randomized phase III trial comparing standard and high-dose pemetrexed as second-line treatment in patients with locally advanced or metastatic non-small-cell lung cancer Ann Oncol 19 939-945