Long-term outcome of patients with vaccine-induced immune thrombotic thrombocytopenia and cerebral venous sinus thrombosis

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作者
Sarah Kehr
Philipp Berg
Susanne Müller
Sarah A. Fiedler
Britta Meyer
Gabriele Ruppert-Seipp
Cornelia Witzenhausen
Marc E. Wolf
Hans H. Henkes
Doris Oberle
Brigitte Keller-Stanislawski
Markus B. Funk
机构
[1] Division Safety of Medicinal Products and Medical Devices,Paul
[2] Klinikum Stuttgart,Ehrlich
[3] Department of Neuroradiology Klinikum Stuttgart,Institut (Federal Institute for Vaccines and Biomedicines)
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npj Vaccines | / 7卷
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摘要
We present the long-term outcomes of 44 patients who developed cerebral venous sinus thrombosis after vaccination with the adenoviral vector ChAdOx1 nCoV-19 COVID-19 vaccine. Assessment of the Extended Glasgow Outcome Scale was performed within 3–6 months after the initial hospital admissions. Patient outcomes ranged from good recovery (13 patients, 29.6%) to moderate disability (11 patients, 25.0%) and severe disability or vegetative state (6 patients, 13.6%). Fatal outcomes were reported in 14 patients (31.8%).
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