Mathematical models for the early detection and treatment of colorectal cancer

被引：19

作者：

Harper P.R. ^{[1
]}

Jones S.K. ^{[2
]}

机构：

[1] School of Mathematics, University of Southampton

[2] Hampshire Isle Wight Strat. Hlth. A., Winchester

来源：

Health Care Management Science | 2005年 / 8卷 / 2期

关键词：

Colorectal cancer; Health care modelling; Screening; Simulation;

D O I：

10.1007/s10729-005-0393-7

中图分类号：

学科分类号：

摘要：

Colorectal cancer is a major cause of death for men and women in the Western world. When the cancer is detected through an awareness of the symptoms by a patient, typically it is at an advanced stage. It is possible to detect cancer at an early stage through screening and the marked differences in survival for early and late stages provide the incentive for the primary prevention or early detection of colorectal cancer. This paper considers mathematical models for colorectal cancer screening together with models for the treatment of patients. Illustrative results demonstrate that detailed attention to the processes involved in diseases, interventions and treatment enable us to combine data and expert knowledge from various sources. Thus a detailed operational model is a very useful tool in helping to make decisions about screening at national and local levels. © 2005 Springer Science + Business Media, Inc.

引用

页码：101 / 109

页数：8

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