Commentary: The prospect of cell-based therapy for epilepsy

被引：0
作者：
Arnold R. Kriegstein
Asla Pitkänen
机构：
[1] University of California,Department of Neurology
[2] Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCSF,Epilepsy Research Laboratory, A.I. Virtanen Institute for Molecular Sciences
[3] University of Kuopio,Department of Neurology
[4] Kuopio University Hospital,undefined
来源：
Neurotherapeutics | 2009年 / 6卷
关键词：
Brain; disease modification; drug-refractory epilepsy; epileptogenesis; genetically-engineered cell lines; transplantation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
About 30% of patient with epilepsy do not respond to available antiepileptic drugs. In addition to seizure suppression, novel approaches are needed to prevent or alleviate epileptogenic process after various types of brain injuries. The use of cell transplants as factories to produce endogeneous anticonvulsants or as bricks to repair abnormal ictogenic and epileptogenic neuronal circuits has generated hope that cell-based therapies could become a novel therapeutic category in the treatment arsenal of epilepsy. Herein we summarize the current status and future perspectives of cell-based therapies in the treatment of epilepsy.
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页码：295 / 299
页数：4
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