Psychogenic polydipsia review: Etiology, differential, and treatment

被引:87
作者
Dundas B. [1 ]
Harris M. [1 ]
Narasimhan M. [1 ]
机构
[1] Department of Neuropsychiatry and Behavioral Sciences, University of South Carolina School of Medicine, Columbia, SC 29203
关键词
Diabetes Insipidus; Ecstasy; Urine Osmolality; Nephrogenic Diabetes Insipidus; Conivaptan;
D O I
10.1007/s11920-007-0025-7
中图分类号
学科分类号
摘要
Psychogenic polydipsia (PPD), a clinical disorder characterized by polyuria and polydipsia, is a common occurrence in inpatients with psychiatric disorders. The underlying pathophysiology of this syndrome is unclear, and multiple factors have been implicated, including a hypothalamic defect and adverse medication effects. Hyponatremia in PPD can progress to water intoxication and is characterized by symptoms of confusion, lethargy, and psychosis, and seizures or death. Evaluation of psychiatric patients with polydipsia warrants a comprehensive evaluation for other medical causes of polydipsia, polyuria, hyponatremia, and the syndrome of inappropriate secretion of antidiuretic hormone. The management strategy in psychiatric patients should include fluid restriction and behavioral and pharmacologic modalities. Copyright © 2007 by Current Medicine Group LLC.
引用
收藏
页码:236 / 241
页数:5
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