Design, synthesis, and biological evaluation of novel N4-substituted sulfonamides: acetamides derivatives as dihydrofolate reductase (DHFR) inhibitors

被引：0
作者：
Essam M. Hussein
Munirah M. Al-Rooqi
Shimaa M. Abd El-Galil
Saleh A. Ahmed
机构：
[1] Umm Al-Qura University,Department of Chemistry, Faculty of Applied Science
[2] Assiut University,Chemistry Department, Faculty of Science
[3] Al-azhar University,Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy (Girls)
来源：
BMC Chemistry | / 13卷
关键词：
Sulfonamide; Anticancer; Antimicrobial; Acetamides; Molecular docking; Structure–activity relationship (SAR); DHFR inhibitors;
D O I：
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