A new function for the RNA-editing enzyme ADAR1

被引:0
|
作者
Hisashi Iizasa
Kazuko Nishikura
机构
[1] The Wistar Institute,Hisashi Iizasa and Kazuko Nishikura are in the Department of Gene Expression and Regulation
[2] Philadelphia,undefined
[3] Pennsylvania 19104,undefined
[4] USA. kazuko@wistar.org,undefined
来源
Nature Immunology | 2009年 / 10卷
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摘要
ADAR1 catalyzes the deamination of adenosine to inosine in double-stranded RNA. This RNA-editing enzyme is now shown to be involved in hematopoiesis, where it acts to suppress interferon signaling and to block premature apoptosis.
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页码:16 / 18
页数:2
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