Development of a high-throughput screen to identify small molecule enhancers of sarcospan for the treatment of Duchenne muscular dystrophy

被引：0
作者：
Cynthia Shu
Ariana N. Kaxon-Rupp
Judd R. Collado
Robert Damoiseaux
Rachelle H. Crosbie
机构：
[1] University of California Los Angeles,Molecular Biology Institute
[2] University of California Los Angeles,Department of Integrative Biology and Physiology
[3] University of California Los Angeles,Center for Duchenne Muscular Dystrophy
[4] University of California Los Angeles,Department of Molecular and Medicinal Pharmacology
[5] University of California Los Angeles,California NanoSystems Institute
[6] University of California Los Angeles,Department of Neurology David Geffen School of Medicine
来源：
Skeletal Muscle | / 9卷
关键词：
Drug discovery; Duchenne muscular dystrophy; C2C12; Dystrophin; Felodipine; High-throughput screen; Sarcolemma; Sarcospan; Small molecules;
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[1]  
Ryder S(2017)The burden, epidemiology, costs and treatment for Duchenne muscular dystrophy: an evidence review Orphanet J Rare Dis 12 79-928
[2]  
Leadley RM(1987)Dystrophin: the protein product of the Duchenne muscular dystrophy locus Cell 51 919-262
[3]  
Armstrong N(1989)Association of dystrophin and an integral membrane glycoprotein Nature 338 259-3714
[4]  
Westwood M(1993)Dystrophin protects the sarcolemma from stresses developed during muscle contraction Proc Natl Acad Sci U S A 90 3710-306
[5]  
de Kock S(2015)Interactions between muscle stem cells, mesenchymal-derived cells and immune cells in muscle homeostasis, regeneration and disease Cell Death Dis 6 e1830-277
[6]  
Butt T(2017)Clinical outcomes in Duchenne muscular dystrophy: a study of 5345 patients from the TREAT-NMD DMD global database J Neuromuscul Dis 4 293-117
[7]  
Hoffman EP(1990)The incidence and evolution of cardiomyopathy in Duchenne muscular dystrophy Int J Cardiol 26 271-319
[8]  
Brown RH(2007)Dystrophin, its interactions with other proteins, and implications for muscular dystrophy Biochim Biophys Acta 1772 108-752
[9]  
Kunkel LM(1990)Deficiency of a glycoprotein component of the dystrophin complex in dystrophic muscle Nature 345 315-508
[10]  
Campbell KP(1990)Glycoprotein complex anchoring dystrophin to sarcolemma J Biochem 108 748-9165
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