Ipsilesional trajectory control is related to contralesional arm paralysis after left hemisphere damage

被引：0
作者：
Kathleen Y. Haaland
Sydney Y. Schaefer
Robert T. Knight
John Adair
Alvaro Magalhaes
Joseph Sadek
Robert L. Sainburg
机构：
[1] New Mexico Veterans Affairs Healthcare System,Research Service (151)
[2] University of New Mexico,Department of Neurology
[3] University of New Mexico,Department of Psychiatry
[4] Washington University,Department of Biomedical Engineering
[5] Washington University,Program in Physical Therapy
[6] University of California,Department of Psychology
[7] University of California,Helen Wills Neuroimaging Center
[8] New Mexico Veterans Affairs Healthcare System,Neurology Service
[9] New Mexico Veterans Affairs Healthcare System,Radiology Service
[10] University of New Mexico,Department of Radiology
[11] New Mexico Veterans Affairs Healthcare System,Behavioral Healthcare Line (116)
[12] The Pennsylvania State University,Department of Kinesiology
[13] The Pennsylvania State University,Department of Neuroscience
[14] The Pennsylvania State University,Department of Bioengineering
[15] The Pennsylvania State University,The Gerontology Center
来源：
Experimental Brain Research | 2009年 / 196卷
关键词：
Paresis, lateralization; Motor control; Stroke; Ipsilateral impairment; Hemisphere; Motor cortex, premotor cortex, motor performance; Hemiparesis; Hemisphere, arm paralysis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We have recently shown ipsilateral dynamic deficits in trajectory control are present in left hemisphere damaged (LHD) patients with paresis, as evidenced by impaired modulation of torque amplitude as response amplitude increases. The purpose of the current study is to determine if these ipsilateral deficits are more common with contralateral hemiparesis and greater damage to the motor system, as evidenced by structural imaging. Three groups of right-handed subjects (healthy controls, LHD stroke patients with and without upper extremity paresis) performed single-joint elbow movements of varying amplitudes with their left arm in the left hemispace. Only the paretic group demonstrated dynamic deficits characterized by decreased modulation of peak torque (reflected by peak acceleration changes) as response amplitude increased. These results could not be attributed to lesion volume or peak velocity as neither variable differed across the groups. However, the paretic group had damage to a larger number of areas within the motor system than the non-paretic group suggesting that such damage increases the probability of ipsilesional deficits in dynamic control for modulating torque amplitude after left hemisphere damage.
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页码：195 / 204
页数：9
相关论文
共 125 条
  • [1] Bagesteiro LB(2003)Nondominant arm advantages in load compensation during rapid elbow joint movements J Neurophysiol 90 1503-1513
  • [2] Sainburg RL(1989)Prehension in the pigeon. II. Kinematic analysis Exp Brain Res 75 577-585
  • [3] Bermejo R(1973)Cerebral control of contralateral and ipsilateral arm, hand and finger movements in the split-brain rhesus monkey Brain 96 653-674
  • [4] Zeigler HP(1973)Self-observations and neuro-anatomical considerations after a stroke Brain 96 675-694
  • [5] Brinkman J(1981)Responses to force perturbations preceding voluntary human arm movements Brain Res 220 350-355
  • [6] Kuypers HG(1990)Movement-related phasic muscle activation. II. Generation and functional role of the triphasic pattern J Neurophysiol 63 465-472
  • [7] Brodal A(1996)Performance of the ‘unaffected’ upper extremity of elderly stroke patients Stroke 27 1564-1570
  • [8] Brown SH(2008)Cortical mechanisms involved in visuomotor coordination during precision walking Brain Res Rev 57 199-211
  • [9] Cooke JD(2007)Lateralization of motor adaptation reveals independence in control of trajectory and steady-state position Exp Brain Res 179 551-561
  • [10] Cooke JD(2000)Deficits in compensatory trajectory adjustments after unilateral sensorimotor stroke Exp Brain Res 132 328-344
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