A prospective study to assess the clinical utility of serum HER2 extracellular domain in breast cancer with HER2 overexpression

被引:0
作者
Nathalie Reix
Charlotte Malina
Marie-Pierre Chenard
Jean-Pierre Bellocq
Stéphanie Delpous
Sébastien Molière
Anthony Sevrin
Karl Neuberger
Catherine Tomasetto
Carole Mathelin
机构
[1] ICube UMR 7357,Laboratoire de Biochimie et Biologie Moléculaire
[2] Université de Strasbourg/CNRS,Unité de Sénologie
[3] Fédération de Médecine Translationnelle de Strasbourg (FMTS),Service de Pathologie
[4] Hôpitaux Universitaires de Strasbourg,Department of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR 7104, INSERM U964
[5] Hôpitaux Universitaires de Strasbourg,Department of Imaging
[6] Hôpitaux Universitaires de Strasbourg,undefined
[7] Université de Strasbourg,undefined
[8] Hôpitaux Universitaires de Strasbourg,undefined
[9] Quantmetry,undefined
来源
Breast Cancer Research and Treatment | 2016年 / 160卷
关键词
Breast cancer; HER2 positive; Extracellular domain ECD; Prognosis factor; Monitoring; Trastuzumab;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:249 / 259
页数:10
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  • [21] McShane LM(2003)Potential clinical utility of serum HER2/neu oncoprotein concentrations in patients with breast cancer Clin Chem 49 1579-1515
  • [22] Sauerbrei W(2006)Predicting tissue HER2 status using serum HER2 levels in patients with metastatic breast cancer Clin Chem 52 1510-4110
  • [23] Lennon S(2012)Relationship between serum HER2 extracellular domain levels, tissue HER2 expression, and clinico-pathological parameters in early stage breast cancer Chin Med J 125 4104-174
  • [24] Barton C(2002)New functions for the matrix metalloproteinases in cancer progression Nat Rev Cancer 2 161-890
  • [25] Banken L(2008)Evaluation of serum HER2 extracellular domain in early breast cancer patients: correlation with clinicopathological parameters and survival Ann Oncol 19 883-658
  • [26] Leary AF(1994)Elevated erbB-2 oncoprotein levels in preoperative and follow-up serum samples define an aggressive disease course in patients with breast cancer Cancer 73 652-284
  • [27] Hanna WM(2012)High serum HER2 extracellular domain levels: correlation with a worse disease-free survival and overall survival in primary operable breast cancer patients J Cancer Res Clin Oncol 138 275-879
  • [28] van de Vijver MJ(1997)Soluble HER-2/neu neutralizes biologic effects of anti-HER-2/neu antibody on breast cancer cells in vitro Int J Cancer 73 875-5129
  • [29] Molina R(1998)NH2-terminally truncated HER-2/neu protein: relationship with shedding of the extracellular domain and with prognostic factors in breast cancer Cancer Res 58 5123-1130
  • [30] Jo J(2004)Monitoring of serum HER2/neu predicts histopathological response to neoadjuvant trastuzumab-based therapy for breast cancer Anticancer Res 24 1127-501