Assessment of the Tolerability and Efficacy of Amlodipine in 9295 Patients with Mild or Moderate Essential Hypertension

被引：0
作者：
A. C. Pessina
M. Gallucci
机构：
[1] University of Padua,Institute of Clinical Medicine
[2] Hospital S. Giovanni,Department of Angiology
来源：
Clinical Drug Investigation | 1997年 / 13卷
关键词：
Diastolic Blood Pressure; Calcium Antagonist; Amlodipine; Antihypertensive Agent; Drug Invest;
D O I：
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学科分类号：
摘要：
An open multicentre study was conducted to evaluate the long term efficacy and tolerability of once-daily amlodipine (5 or 10mg for up to 24 weeks) in 9295 patients with mild or moderate essential hypertension. After a 2-week washout period, patients began treatment with amlodipine 5 mg/day, and this could be increased to 10 mg/day in patients showing inadequate blood pressure control after 2 weeks. If acceptable control was not achieved after 6 weeks of treatment with amlodipine alone, a second antihypertensive agent could be added (diuretic, ACE inhibitor or β-blocker). Data were analysed for the population as a whole, as well as for 2 subgroups based on age (group I: ≤ 65 years; group II: > 65 years).
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页码：137 / 142
页数：5
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