Adherence to Highly Active Antiretroviral Therapy Among Children in Ethiopia: A Systematic Review and Meta-analysis

被引：0
作者：
Aklilu Endalamaw
Nega Tezera
Setegn Eshetie
Sintayehu Ambachew
Tesfa Dejenie Habtewold
机构：
[1] University of Gondar,Department of Pediatrics and Child Health Nursing, School of Nursing, College of Medicine and Health Sciences
[2] University of Gondar,Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences
[3] University of Gondar,Department of Clinical Chemistry, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences
[4] University of Groningen,University Center for Psychiatry, Rob Giel Research Centre
[5] University Medical Center Groningen,Department of Epidemiology
[6] University of Groningen,undefined
[7] University Medical Center Groningen,undefined
来源：
AIDS and Behavior | 2018年 / 22卷
关键词：
Adherence; Antiretroviral therapy; Children; Highly active; HIV; Medication; Meta-analysis; Ethiopia; Adherencia; Terapia antirretroviral altamente activa; Niños; VIH; Medicamentos; Meta-análisis; Etiopía;
D O I：
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中图分类号：
学科分类号：
摘要：
Adherence to highly active antiretroviral therapy (HAART) is the mainstay of the strategy in reducing morbidity and mortality of HIV-infected children. Different primary studies were conducted in Ethiopia. Thus, we aimed to conduct a meta-analysis of the national prevalence of optimal adherence to HAART in children. In addition, associated factors of HAART adherence were reviewed. A weighted inverse variance random-effects model was applied. The 88.7 and 93.7% of children were adhering to HAART at 07 and 03 days prior to an interview respectively. The subgroup analysis showed that HAART adherence was 93.4% in Amhara, 90.1% in Addis Ababa and 87.3% in Tigray at 07 days prior to an interview. Our study suggests that, within short window reported time, adherence to HAART in Ethiopian children may be in a good progress. Emphasis on specific adherence interventions need further based on individual predictors to improve overall HAART adherence of children.
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页码：2513 / 2523
页数：10
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