IDH1 R132C mutation is detected in clear cell hepatocellular carcinoma by pyrosequencing

[1] Jennings GT(1994)Cytosolic NADP (+)-dependent isocitrate dehydrogenase. Isolation of rat cDNA and study of tissue-specific and developmental expression of mRNA J Biol Chem 269 23128-23134

[2] Sechi S(2010)Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism J Natl Cancer Inst 102 932-41

[3] Stevenson PM(2013)What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer Genes Dev 27 836-52

[4] Tuckey RC(2009)Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers Int J Cancer 125 353-5

[5] Parmelee D(2010)Cancer-associated IDH mutations: biomarker and therapeutic opportunities Oncogene 29 6409-17

[6] McAlister-Henn L(2012)Isocitrate dehydrogenase 1 and 2 mutations in cholangiocarcinoma Hum Pathol 43 1552-8

[7] Reitman ZJ(2013)Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas Oncogene 32 3091-100

[8] Yan H(2012)Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping Oncologist 17 72-9

[9] Losman J-A(2013)Cancer Digital Slide Archive: an informatics resource to support integrated in silico analysis of TCGA pathology data J Am Med Inform Assoc 20 1091-8

[10] Kaelin WG(2014)IDH1 p.R132 mutations may not be actively involved in the carcinogenesis of hepatocellular carcinoma Med Sci Monit 20 247-54

[1] Jennings GT(1994)Cytosolic NADP (+)-dependent isocitrate dehydrogenase. Isolation of rat cDNA and study of tissue-specific and developmental expression of mRNA J Biol Chem 269 23128-23134

[2] Sechi S(2010)Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism J Natl Cancer Inst 102 932-41

[3] Stevenson PM(2013)What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer Genes Dev 27 836-52

[4] Tuckey RC(2009)Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers Int J Cancer 125 353-5

[5] Parmelee D(2010)Cancer-associated IDH mutations: biomarker and therapeutic opportunities Oncogene 29 6409-17

[6] McAlister-Henn L(2012)Isocitrate dehydrogenase 1 and 2 mutations in cholangiocarcinoma Hum Pathol 43 1552-8

[7] Reitman ZJ(2013)Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas Oncogene 32 3091-100

[8] Yan H(2012)Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping Oncologist 17 72-9

[9] Losman J-A(2013)Cancer Digital Slide Archive: an informatics resource to support integrated in silico analysis of TCGA pathology data J Am Med Inform Assoc 20 1091-8

[10] Kaelin WG(2014)IDH1 p.R132 mutations may not be actively involved in the carcinogenesis of hepatocellular carcinoma Med Sci Monit 20 247-54