Comparison between optical coherence tomography angiography and fluorescein angiography findings in retinal vasculitis

被引：36
作者：
Abucham-Neto J.Z. [1 ,2 ]
Torricelli A.A.M. [3 ]
Lui A.C.F. [1 ,4 ]
Guimarães S.N. [1 ]
Nascimento H. [1 ]
Regatieri C.V. [1 ]
机构：
[1] Departamento de Oftalmologia, Universidade Federal de São Paulo, Rua Botucatu, 821, Vila Clementino, São Paulo, SP
[2] Departamento de Oftalmologia, Faculdade de Medicina do ABC, São Paulo
[3] Departamento de Oftalmologia, Universidade de São Paulo, São Paulo
[4] Departamento de Oftalmologia, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo
来源：
International Journal of Retina and Vitreous | / 4卷 / 1期
关键词：
Angiofluoresceinography; Behçet; En Face; OCT angiography; Retinal vasculitis; Sarcoidosis; Takayashi arteritis; Toxoplasmosis; Uveitis;
D O I：
10.1186/s40942-018-0117-z
中图分类号：
学科分类号：
摘要：
Background: To describe optical coherence tomography angiography (OCT-A) findings in patients with retinal vasculitis and to compare them to current fluorescein angiography (FA) findings. Methods: This was an observational case series. Nineteen eyes in 10 patients with retinal vasculitis of various etiologies were imaged with FA (TRC-50DX, Topcon) and OCT-A (SD-OCT, Optovue). The images were reviewed and analyzed. Results: The mean age was 36 years (range 24-67 years); there were three males and seven females. The primary vessels involved were veins (89%). Fourteen eyes (74%) had active inflammatory disease during the study period, with signs of vascular sheathing and perivascular leakage on FA. Interestingly, in this group, OCT-A was not able to detect clear signs of active inflammation around the affected vessels. Nevertheless, OCT-A was able to detect secondary lesions in fourteen eyes (74%), including some findings not clearly shown on FA. Most of these were within the macular area. OCT-A was particularly effective in cases of capillary dropout, increased foveal avascular zone, telangiectasias, shunts, and areas of neovascularization. Conclusion: FA remains an essential complementary exam for detection of retinal vasculitis. However, OCT-A extends FA findings and affords better assessment of secondary complications. © The Author(s) 2018.
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