Prospective evaluation of insulin and incretin dynamics in obese adults with and without diabetes for 2 years after Roux-en-Y gastric bypass

被引：0
作者：
Jonathan Q. Purnell
Geoffrey S. Johnson
Abdus S. Wahed
Chiara Dalla Man
Francesca Piccinini
Claudio Cobelli
Ronald L. Prigeon
Bret H. Goodpaster
David E. Kelley
Myrlene A. Staten
Karen E. Foster-Schubert
David E. Cummings
David R. Flum
Anita P. Courcoulas
Peter J. Havel
Bruce M. Wolfe
机构：
[1] Oregon Health & Science University,Department of Medicine, The Knight Cardiovascular Institute, Mailcode MDYMI
[2] University of Pittsburgh,Graduate School of Public Health
[3] University of Padova,Department of Information Engineering
[4] VA Maryland Health Care System,Department of Medicine
[5] Translational Research Institute for Metabolism and Diabetes,Department of Surgery
[6] Sanford-Burnham Institute,Department of Surgery
[7] Merck & Co.,Departments of Molecular Biosciences and Nutrition
[8] National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK),Department of Surgery
[9] University of Washington,undefined
[10] University of Washington,undefined
[11] University of Pittsburgh,undefined
[12] University of California,undefined
[13] Davis,undefined
[14] Oregon Health & Science University,undefined
来源：
Diabetologia | 2018年 / 61卷
关键词：
Disposition index; Frequently-sampled intravenous glucose tolerance test; Gastric bypass; GIP; GLP-1; Glucagon; Insulin secretion; Insulin sensitivity; Lipids; Meal test; Obesity; Proinsulin; Remission;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1142 / 1154
页数：12
相关论文
共 151 条
[1]  
Pories WJ(1992)Surgical treatment of obesity and its effect on diabetes: 10-y follow-up Am J Clin Nutr 55 582S-585S
[2]  
MacDonald KG(2016)Type 2 diabetes remission rates after laparoscopic gastric bypass and gastric banding: results of the Longitudinal Assessment of Bariatric Surgery Study Diabetes Care 39 1101-1107
[3]  
Morgan EJ(2017)Bariatric surgery versus intensive medical therapy for diabetes -- 5-year outcomes N Engl J Med 376 641-651
[4]  
Purnell JQ(2010)Improvement in peripheral glucose uptake after gastric bypass surgery is observed only after substantial weight loss has occurred and correlates with the magnitude of weight lost J Gastrointest Surg 14 15-23
[5]  
Selzer F(2012)Gastric bypass and banding equally improve insulin sensitivity and beta cell function J Clin Invest 122 4667-4674
[6]  
Wahed AS(2013)Long-term effects of bariatric surgery on meal disposal and β-cell function in diabetic and nondiabetic patients Diabetes 62 3709-3717
[7]  
Schauer PR(2001)The importance of β-cell failure in the development and progression of type 2 diabetes J Clin Endocrinol Metab 86 4047-4058
[8]  
Bhatt DL(2013)Weight change and health outcomes at 3 years after bariatric surgery among individuals with severe obesity JAMA 310 2416-2425
[9]  
Kirwan JP(2014)β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment Diabetes Care 37 1751-1758
[10]  
Campos GM(2007)Safety and efficacy of bariatric surgery: Longitudinal Assessment of Bariatric Surgery Surg Obes Relat Dis 3 116-126
12345678910