Cloning of tunicamycin biosynthetic gene cluster from Streptomyces chartreusis NRRL 3882

被引：0
作者：
Suman Karki
So-Yeon Kwon
Hyung-Jin Kwon
机构：
[1] Myongji University,Department of Biological Science, Division of Bioscience and Bioinformatics
来源：
Journal of the Korean Society for Applied Biological Chemistry | 2011年 / 54卷
关键词：
biosynthetic gene cluster; gene inactivation; tunicamycin;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The putative tunicamycin biosynthetic gene cluster was identified in Streptomyces clavuligerus with genome mining approach and this genetic information was used to isolate the tunicamycin biosynthetic gene set from S. chartreusis. Gene inactivation of tun1Sch abolished tunicamycin accumulation in S. chartreusis, confirming that the tunicamycin biosynthetic gene cluster was cloned.
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页码：136 / 140
页数：4
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