MetaReg: a platform for modeling, analysis and visualization of biological systems using large-scale experimental data

被引:0
|
作者
Igor Ulitsky
Irit Gat-Viks
Ron Shamir
机构
[1] Tel Aviv University,School of Computer Science
[2] Max Planck Institute for Molecular Genetics,Computational Molecular Biology Department
来源
Genome Biology | / 9卷
关键词
Additional Data File; Rapamycin Treatment; High Throughput Data; Regulatory Logic; Model Canvas;
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摘要
MetaReg http://acgt.cs.tau.ac.il/metareg/application.html is a computational tool that models cellular networks and integrates experimental results with such models. MetaReg represents established knowledge about a biological system, available today mostly in informal form in the literature, as probabilistic network models with underlying combinatorial regulatory logic. MetaReg enables contrasting predictions with measurements, model improvements and studying what-if scenarios. By summarizing prior knowledge and providing visual and computational aids, it helps the expert explore and understand her system better.
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