Dendritic cells transfected with heat-shock protein 70 messenger RNA for patients with hepatitis C virus-related hepatocellular carcinoma: a phase 1 dose escalation clinical trial

被引：0
|
作者：
Yoshinari Maeda
Kiyoshi Yoshimura
Hiroto Matsui
Yoshitaro Shindo
Takao Tamesa
Yukio Tokumitsu
Noriaki Hashimoto
Yoshihiro Tokuhisa
Kazuhiko Sakamoto
Kouhei Sakai
Yutaka Suehiro
Yuji Hinoda
Koji Tamada
Shigefumi Yoshino
Shoichi Hazama
Masaaki Oka
机构：
[1] Yamaguchi University Graduate School of Medicine,Department of Digestive Surgery and Surgical Oncology
[2] Yamaguchi University Graduate School of Medicine,Department of Oncology and Laboratory Medicine
[3] Yamaguchi University Graduate School of Medicine,Department of Immunology and Cell Signaling Analysis
来源：
Cancer Immunology, Immunotherapy | 2015年 / 64卷
关键词：
Hepatocellular carcinoma; Heat-shock protein 70; Dendritic cell; Immunotherapy; Electroporation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1047 / 1056
页数：9
相关论文
共 50 条
  • [41] Altered cytokine levels and increased CD4+CD57+ T cells in the peripheral blood of hepatitis C virus-related hepatocellular carcinoma patients
    Shiraki, Tatsuya
    Takayama, Eiji
    Magari, Hirohito
    Nakata, Takahiro
    Maekita, Takao
    Enomoto, Shotaro
    Mori, Yoshiyuki
    Shingaki, Naoki
    Moribata, Kosaku
    Deguchi, Hisanobu
    Ueda, Kazuki
    Inoue, Izumi
    Mizuno-Kamiya, Masako
    Yashiro, Koji
    Iguchi, Mikitaka
    Tamai, Hideyuki
    Kameyama, Yasunaga
    Kato, Jun
    Kondoh, Nobuo
    Ichinose, Masao
    ONCOLOGY REPORTS, 2011, 26 (01) : 201 - 208
  • [42] Survey of survival among patients with hepatitis C virus-related hepatocellular carcinoma treated with peretinoin, an acyclic retinoid, after the completion of a randomized, placebo-controlled trial
    Kiwamu Okita
    Namiki Izumi
    Kenji Ikeda
    Yukio Osaki
    Kazushi Numata
    Masafumi Ikeda
    Norihiro Kokudo
    Kazuho Imanaka
    Shuhei Nishiguchi
    Shunsuke Kondo
    Yoichi Nishigaki
    Susumu Shiomi
    Kazuomi Ueshima
    Norio Isoda
    Yoshiyasu Karino
    Masatoshi Kudo
    Katsuaki Tanaka
    Shuichi Kaneko
    Hisataka Moriwaki
    Masatoshi Makuuchi
    Takuji Okusaka
    Norio Hayashi
    Yasuo Ohashi
    Hiromitsu Kumada
    Journal of Gastroenterology, 2015, 50 : 667 - 674
  • [43] Survey of survival among patients with hepatitis C virus-related hepatocellular carcinoma treated with peretinoin, an acyclic retinoid, after the completion of a randomized, placebo-controlled trial
    Okita, Kiwamu
    Izumi, Namiki
    Ikeda, Kenji
    Osaki, Yukio
    Numata, Kazushi
    Ikeda, Masafumi
    Kokudo, Norihiro
    Imanaka, Kazuho
    Nishiguchi, Shuhei
    Kondo, Shunsuke
    Nishigaki, Yoichi
    Shiomi, Susumu
    Ueshima, Kazuomi
    Isoda, Norio
    Karino, Yoshiyasu
    Kudo, Masatoshi
    Tanaka, Katsuaki
    Kaneko, Shuichi
    Moriwaki, Hisataka
    Makuuchi, Masatoshi
    Okusaka, Takuji
    Hayashi, Norio
    Ohashi, Yasuo
    Kumada, Hiromitsu
    JOURNAL OF GASTROENTEROLOGY, 2015, 50 (06) : 667 - 674
  • [44] Phase 1B, randomized, double-blind, dose-escalation trial of CPG 10101 in patients with chronic hepatitis c virus
    McHutchison, John G.
    Bacon, Bruce R.
    Gordon, Stuart C.
    Lawitz, Eric
    Shiffman, Mitchefl
    Afdhal, Nezam H.
    Jacobson, Ira M.
    Muir, Andrew
    Al-Adhami, Mohammed
    Morris, Mary L.
    Lekstrom-Himes, Julie A.
    Lekstrom-Himes, A.
    Efler, Susan M.
    Davis, Heather L.
    HEPATOLOGY, 2007, 46 (05) : 1341 - 1349
  • [45] PD-1+ TIGIT+ CD8+ T cells are associated with pathogenesis and progression of patients with hepatitis B virus-related hepatocellular carcinoma
    Liu, Xiaoli
    Li, Mengge
    Wang, Xinhui
    Dang, Zhibo
    Jiang, Yuyong
    Wang, Xianbo
    Kong, Yaxian
    Yang, Zhiyun
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 2019, 68 (12) : 2041 - 2054
  • [46] PD-1+ TIGIT+ CD8+ T cells are associated with pathogenesis and progression of patients with hepatitis B virus-related hepatocellular carcinoma
    Xiaoli Liu
    Mengge Li
    Xinhui Wang
    Zhibo Dang
    Yuyong Jiang
    Xianbo Wang
    Yaxian Kong
    Zhiyun Yang
    Cancer Immunology, Immunotherapy, 2019, 68 : 2041 - 2054
  • [47] Overexpression of a DEAD box/RNA helicase protein, rck/p54, in human hepatocytes from patients with hepatitis C virus-related chronic hepatitis and its implication in hepatocellular carcinogenesis
    Miyaji, K
    Nakagawa, Y
    Matsumoto, K
    Yoshida, H
    Morikawa, H
    Hongou, Y
    Arisaka, Y
    Kojima, H
    Inoue, T
    Hirata, I
    Katsu, K
    Akao, Y
    JOURNAL OF VIRAL HEPATITIS, 2003, 10 (04) : 241 - 248
  • [48] Overexpressed cyclo-oxygenase-2 in the background liver is associated with the clinical course of hepatitis C virus-related cirrhosis patients after curative surgery for hepatocellular carcinoma
    Morinaga, Soichiro
    Tarao, Kazuo
    Yamamoto, Yuji
    Nakamura, Yoshiyasu
    Rino, Yasushi
    Miyakawa, Kaoru
    Ohkawa, Shinichi
    Akaike, Makoto
    Sugimasa, Yukio
    Takemiya, Shoji
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2007, 22 (08) : 1249 - 1255
  • [49] PHASE II CLINICAL TRIAL OF THE CTLA-4-BLOCKING MAB TREMELIMUMAB IN PATIENTS WITH HEPATOCELLULAR CARCINOMA (HCC) AND CHRONIC HEPATITIS C VIRUS (HCV) INFECTION
    Sangro, Bruno
    Gomez-Martin, Carlos
    De la Mata, Manuel
    Inarrairaegui, Mercedes
    Garralda, Elena
    Barrera Baena, Pilar
    Riezu-Boj, Jose I.
    Larrea, Esther
    Sarobe, Pablo
    Lasarte, Juan J.
    Luis Perez-Gracia, Jose
    Melero, Ignacio
    Prieto, Jesus
    HEPATOLOGY, 2011, 54 : 496A - 496A
  • [50] Safety, Tolerability, and Preliminary Efficacy of the Anti-Fibrotic Small Molecule PRI-724, a CBP/β-Catenin Inhibitor, in Patients with Hepatitis C Virus-related Cirrhosis: A Single-Center, Open-Label, Dose Escalation Phase 1 Trial
    Kimura, Kiminori
    Ikoma, Akemi
    Shibakawa, Maki
    Shimoda, Shinji
    Harada, Kenichi
    Saio, Masanao
    Imamura, Jun
    Osawa, Yosuke
    Kimura, Masamichi
    Nishikawa, Koji
    Okusaka, Takuji
    Morita, Satoshi
    Inoue, Kazuaki
    Kanto, Tatsuya
    Todaka, Koji
    Nakanishi, Yoichi
    Kohara, Michinori
    Mizokami, Masashi
    EBIOMEDICINE, 2017, 23 : 79 - 87
12345