Solid-State 13C Nuclear Magnetic Resonance Spectroscopic Study on Amorphous Solid Complexes of Tolbutamide with 2-Hydroxypropyl-α-and -β-Cyclodextrins

被引:0
作者
Kenya Kimura
Fumitoshi Hirayama
Hidetoshi Arima
Kaneto Uekama
机构
[1] Kumamoto University,Faculty of Pharmaceutical Sciences
来源
Pharmaceutical Research | 1999年 / 16卷
关键词
tolbutamide; 2-hydroxypropyl cyclodextrins; inclusion complex; amorphous solid; solid-state ; C NMR spectroscopy;
D O I
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中图分类号
学科分类号
摘要
Purpose. The objective of the study was to obtain structural information of inclusion complexes of tolbutamide with HP-α- and -β-cyclo-dextrins in amorphous state.
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页码:1729 / 1734
页数:5
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