Enhanced In Vitro Oligonucleotide and Plasmid DNA Transport by VP1 Virus-like Particles

被引：0
作者：
S. Henke
A. Rohmann
W.M. Bertling
Th. Dingermann
A. Zimmer
机构：
[1] Biocenter—Johann Wolfgang Goethe-University,Institute for Pharmaceutical Technology
[2] Institute for Pharmaceutical Biology,Institute for Pharmaceutical Technology
[3] Gesellschaft für Molekulare Medizin,undefined
[4] Institute for Pharmaceutical Biology,undefined
[5] Biocenter—Johann Wolfgang Goethe-University,undefined
来源：
Pharmaceutical Research | 2000年 / 17卷
关键词：
polyoma virus; VP1 capsoids; NIH 3T3 cells; DNA uptake; EGFP; plasmid transfection;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. We developed a prokaryotic expression system to express the major capsid protein of Polyomavirus, VP1. Furthermore, we investigated the transport of single stranded (ss) and double stranded (ds) DNA, mediated through VP1 as drug delivery system into mouse fibroblasts.
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页码：1062 / 1070
页数：8
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