α-synuclein interacts with SOD1 and promotes its oligomerization

被引:0
|
作者
Anika M. Helferich
Wolfgang P. Ruf
Veselin Grozdanov
Axel Freischmidt
Marisa S. Feiler
Lisa Zondler
Albert C. Ludolph
Pamela J. McLean
Jochen H. Weishaupt
Karin M. Danzer
机构
[1] Ulm University,Department of Neurology
[2] Mayo Clinic,undefined
关键词
Alpha synuclein; SNCA; SOD1; ALS; Parkinson’s disease; Cross-seeding; Oligomers;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] Discovery of a novel homozygous SOD1 truncating variant bolsters infantile SOD1 deficiency syndrome
    Dogan, Mustafa
    Terali, Kerem
    Eroz, Recep
    Kilic, Hueseyin
    Gezdirici, Alper
    Gonullu, Burcin
    MOLECULAR BIOLOGY REPORTS, 2024, 51 (01)
  • [42] Accumulation of dysfunctional SOD1 protein in Parkinson’s disease is not associated with mutations in the SOD1 gene
    Benjamin G. Trist
    Jennifer A. Fifita
    Sarah E. Freckleton
    Dominic J. Hare
    Simon J. G. Lewis
    Glenda M. Halliday
    Ian P. Blair
    Kay L. Double
    Acta Neuropathologica, 2018, 135 : 155 - 156
  • [43] Examination of SOD1 aggregation modulators and their effect on SOD1 enzymatic activity as a proxy for potential toxicity
    Malik, Ravinder
    Corrales, Christian
    Linsenmeier, Miriam
    Alalami, Huda
    Sepanj, Niki
    Bitan, Gal
    FASEB JOURNAL, 2020, 34 (09): : 11957 - 11969
  • [44] Changes in hydrophobicity mainly promotes the aggregation tendency of ALS associated SOD1 mutants
    Tompa, Dharma Rao
    Kadhirvel, Saraboji
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 145 : 904 - 913
  • [45] Infantile SOD1 deficiency syndrome caused by a homozygous SOD1 variant with absence of enzyme activity
    Ezer, Shlomit
    Daana, Muhannad
    Park, Julien H.
    Yanovsky-Dagan, Shira
    Nordstrom, Ulrika
    Basal, Adily
    Edvardson, Simon
    Saada, Ann
    Otto, Markus
    Meiner, Vardiella
    Marklund, Stefan L.
    Andersen, Peter Munch
    Harel, Tamar
    BRAIN, 2022, 145 (03) : 872 - 878
  • [46] Exploratory activity and motor coordination in wild-type SOD1/SOD1 transgenic mice
    Lalonde, R
    Le Pêcheur, M
    Strazielle, C
    London, J
    BRAIN RESEARCH BULLETIN, 2005, 66 (02) : 155 - 162
  • [47] Erythrocyte SOD1 activity, but not SOD1 polymorphisms, is associated with ICU mortality in patients with septic shock
    Costa, Nara Aline
    Cunha, Natalia Baraldi
    Gut, Ana Lucia
    Azevedo, Paula Schmidt
    Polegato, Bertha Furlan
    Mamede Zornoff, Leonardo Antonio
    Rupp de Paiva, Sergio Alberto
    Reis, Bruna Zavarize
    Henrique Fernandes, Ana Angelica
    Rogero, Marcelo Macedo
    Norde, Marina Maintinguer
    Minicucci, Marcos Ferreira
    FREE RADICAL BIOLOGY AND MEDICINE, 2018, 124 : 199 - 204
  • [48] Respiratory Directed Gene Therapy to Silence SOD1 Prolongs Survival in the SOD1 ALS Mouse
    Keeler, Allison M.
    Zieger, Marina
    Semple, Carson
    Veinbachs, Ali
    Gao, Guangping
    Brown, Robert H.
    Mueller, Christian
    ElMallah, Mai K.
    MOLECULAR THERAPY, 2019, 27 (04) : 422 - 422
  • [49] Acylation of SOD1 Provides Tool to determine if Mitochondrial Aggregation of SOD1 is Main Driver of ALS
    Banks, Courtney
    Rodriguez, Nathan
    Gashler, Kyle
    Bikman, Benjamin
    Andersen, Joshua
    FASEB JOURNAL, 2016, 30
  • [50] Propagated misfolding of SOD1 in ALS
    Cashman, Neil
    Grad, Leslie
    Guest, Will
    Yanai, Anat
    Pokrishevsky, Eddie
    O'Neill, Megan
    Silverman, Judith
    Gibbs, Ebrima
    Yousefi, Masoud
    PRION, 2012, 6 : 12 - 12