[1] University of Leicester and the NIHR Leicester Cardiovascular Biomedical Research Unit,Department of Cardiovascular Sciences
[2] University Hospitals of Leicester NHS Trust,Multidisciplinary Cardiovascular Research Centre and The Division of Cardiovascular and Diabetes Research
[3] Glenfield Hospital,Harefield Hospital, Royal Brompton and Harefield Foundation Trust
[4] Leeds Institute of Cardiovascular and Metabolic Medicine,Leicester Clinical Trials Unit, University of Leicester, UK and Department of Mathematical Statistics and Actuarial Science
[5] University of Leeds,The Heart Hospital
[6] NIHR Cardiovascular Biomedical Research Unit,undefined
[7] University Hospital Southampton NHS Foundation Trust and University of Southampton,undefined
[8] Kettering General Hospital,undefined
[9] Royal Derby Hospital,undefined
[10] University of Leicester,undefined
[11] University of the Free State,undefined
[12] Norfolk and Norwich University Hospitals NHS Foundation Trust and Norwich Medical School,undefined
[13] University of East Anglia,undefined
[14] University College London Hospitals,undefined