The molecular biology of pelvi-ureteric junction obstruction

被引：0
|
作者：
Laura Jackson
Mark Woodward
Richard J. Coward
机构：
[1] University of Bristol,Bristol Renal Group
[2] Bristol Royal Hospital for Children,undefined
来源：
Pediatric Nephrology | 2018年 / 33卷
关键词：
Pelvi-ureteric junction obstruction; Aetiology; Molecular biology; Biomarker; Hydronephrosis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Over recent years routine ultrasound scanning has identified increasing numbers of neonates as having hydronephrosis and pelvi-ureteric junction obstruction (PUJO). This patient group presents a diagnostic and management challenge for paediatric nephrologists and urologists. In this review we consider the known molecular mechanisms underpinning PUJO and review the potential of utilising this information to develop novel therapeutics and diagnostic biomarkers to improve the care of children with this disorder.
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页码：553 / 571
页数：18
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