PIK3CA oncogenic mutations represent a major mechanism of resistance to trastuzumab in HER2/neu overexpressing uterine serous carcinomas

被引:0
作者
Jonathan D Black
Salvatore Lopez
Emiliano Cocco
Stefania Bellone
Gary Altwerger
Carlton L Schwab
Diana P English
Elena Bonazzoli
Federica Predolini
Francesca Ferrari
Elena Ratner
Dan-Arin Silasi
Masoud Azodi
Peter E Schwartz
Alessandro D Santin
机构
[1] Gynecology and Reproductive Sciences Yale University School of Medicine,Department of Obstetrics
[2] University Campus Bio-Medico of Rome,Division of Gynecologic Oncology, Department of Obstetrics and Gynecology
来源
British Journal of Cancer | 2015年 / 113卷
关键词
uterine serous carcinoma; HER2/neu; PIK3CA; targeted therapy; trastuzumab;
D O I
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页码:1020 / 1026
页数:6
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