Polymethylene Derivatives of Nucleic Bases with ω-Functional Groups: II. Adenine and Hypoxanthine Derivatives

被引：0
作者：
A. A. Makinsky
A. M. Kritzyn
E. A. Ul'yanova
O. D. Zakharova
D. V. Bugreev
G. A. Nevinsky
机构：
[1] Russian Academy of Sciences,Engelhardt Institute of Molecular Biology
[2] Russian Academy of Sciences,Novosibirsk Institute of Bioorganic Chemistry, Siberian Division
来源：
Russian Journal of Bioorganic Chemistry | 2001年 / 27卷
关键词：
nucleosides; polymethylene analogues; alkylation; HIV reverse transcriptase; human DNA topoisomerase I;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
N9-Polymethylene derivatives of adenine and hypoxanthine with various functional groups in the ω-position of the alkyl substituent were synthesized. Their physicochemical properties and effect on the HIV reverse transcriptase and DNA topoisomerase I were studied.
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页码：167 / 172
页数：5
相关论文
共 72 条
[11]  
Imbach J.-L.(1995)undefined FEBS Lett. 373 255-258
[12]  
Meszarosova K.(1995)undefined FEBS Lett. 368 97-100
[13]  
Holy A.(1998)undefined Biochimie 80 303-308
[14]  
Masojidkova M.(1992)undefined Eur. J. Biochem. 207 351-358
[15]  
Tarrago-Litvak L.(undefined)undefined undefined undefined undefined-undefined
[16]  
Andreola M.L.(undefined)undefined undefined undefined undefined-undefined
[17]  
Nevinsky G.A.(undefined)undefined undefined undefined undefined-undefined
[18]  
Sarish-Cottin L.(undefined)undefined undefined undefined undefined-undefined
[19]  
Litvak S.(undefined)undefined undefined undefined undefined-undefined
[20]  
Pommier Y.(undefined)undefined undefined undefined undefined-undefined
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