Expression Patterns of ER, HER2, and NM23-H1 in Breast Cancer Patients with Different Menopausal StatusCorrelations with Metastasis

被引:0
作者
Su-Wei Dong
Lin Wang
Jun Sui
Xi-Yun Deng
Xiao-Dan Chen
Zhi-Wei Zhang
Xu Liu
Zhi-Min Liu
Jian-Hua Zhang
Qi-Sheng Yang
Yong-Feng Jia
Xin Song
机构
[1] Third Affiliated Hospital of Kunming School of Medicine (Tumor Hospital of Yunnan Province),Department of Cancer Biotherapy Center
[2] Center for Disease Control and Prevention,Department of Surgery
[3] University of Texas Medical School,Department of Biomedical Engineering Research Center
[4] Kunming School of Medicine,Department of Pathology
[5] Third Affiliated Hospital of Kunming School of Medicine (Tumor Hospital of Yunnan Province),undefined
[6] First Affiliated Hospital of Inner Mongolia School of Medicine,undefined
来源
Molecular Diagnosis & Therapy | 2011年 / 15卷
关键词
Estrogen Receptor; Menopausal Status; Invasive Ductal Carcinoma; HER2 Expression; Estrogen Receptor Expression;
D O I
暂无
中图分类号
学科分类号
摘要
Objective: This study was designed to analyze expression patterns of estrogen receptor (ER), human epidermal growth factor receptor-2 (HER2/ERBB2), and nonmetastatic protein 23 (NM23-H1/NME1) proteins in patients with invasive ductal carcinoma and different menopausal status to identify their relationships with axillary lymph node metastasis.
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页码:211 / 219
页数:8
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  • [1] Jemal A(2008)Cancer statistics, 2008 CA Cancer J Clin 58 71-96
  • [2] Siegel R(2005)Global cancer statistics, 2002 CA Cancer J Clin 55 74-108
  • [3] Ward E(1997)Association of body mass index, physical activity, and reproductive histories with breast cancer: a case-control study in Gifu, Japan Breast Cancer Res Treat 43 65-72
  • [4] Parkin DM(1999)Risk factors for breast cancer in Japan, with special attention to anthropometric measurements and reproductive history Jpn J Clin Oncol 29 137-46
  • [5] Bray F(2002)Do estrogens always increase breast cancer risk? J Steroid Biochem Mol Biol 80 163-74
  • [6] Ferlay J(2002)Activation of antimetastatic Nm23-H1 gene expression by estrogen and its alpha-receptor Endocrinology 143 467-75
  • [7] Hu YH(1990)Hormonal modulation of HER-2/neu protooncogene messenger ribonucleic acid and p185 protein expression in human breast cancer cell lines Cancer Res 50 3947-51
  • [8] Chisato N(2001)HER2 as a prognostic factor in breast cancer Oncology 61 67-72
  • [9] Hiroyuki S(2005)Can molecular markers predict when to implement treatment with aromatase inhibitors in invasive breast cancer? Clin Cancer Res 11 4835-42
  • [10] Tung HT(2000)Molecular mechanisms underlying ErbB2/HER2 action in breast cancer Oncogene 19 6102-14