Preparation of vinyl thymidine ester catalyzed by protease and its chemical polymerization

被引：0
作者：
Masaru Kitagawa
Hong Fan
Takao Raku
Ryuichiro Kurane
Yutaka Tokiwa
机构：
[1] National Institute of Bioscience and Human-Technology,
[2] Konan Chemical Industry Co.,undefined
[3] Ltd.,undefined
[4] Takatsuki,undefined
来源：
Biotechnology Letters | 2000年 / 22卷
关键词：
alkaline protease; polymerization; sp.; thymidine; vinyl ester;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Transesterification reaction of 0.25 M thymidine with 1 M divinyladipate in dimethylformamide (DMF) was catalyzed by an alkaline protease (5 mg ml−1) from Streptomyces sp. (20 units mg−1 min) at 30 °C for 7 days to give 5′-O-vinyladipoyl thymidine (yield 77%) without formation of any by-products. Poly(vinyl alcohol) containing thymidine branches could be obtained by its free-radical polymerization.
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页码：883 / 886
页数：3
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